The Hotel Regina Opera - Astotel Paris is within walking distance of the Pompidou Centre, the Opera House, and the major shopping galleries, in what is known as the Grands Boulevards area. Located on a street between the Bastille and Opera districts, the hotel is also convenient to Sacre Couer and Place de la Bastille. The Hotel Regina Opera - Astotel Paris is 23 km from Charles de Gaulle International Airport, and 1 km from the east train station. It is within walking distance of major metro stops.

There are 44 rooms available. The Hotel Regina Opera - Astotel Paris is fully air conditioned. Wireless Internet access is available in all of the rooms. Rooms have cable TV, telephones, private bathrooms with hairdryers, and in-room safes. Most rooms are singles, and all have light colored furniture with large windows designed to let in natural light.

The Hotel Regina Opera - Astotel Paris was completely renovated in 2003. It has contemporary décor, and a large lobby area with lounge. Breakfast service is offered daily in the designated breakfast room.